Annotation Detail

Information
Associated Genes
ANPEP
Associated Variants
ANPEP UNKNOWN
Source Database
MMMP
Description
NGR peptide is a ligand for CD13, which is expressed by tumor vessels. NGR-TNF is a peptide-TNF conjugate able to target tumor blood vessels
MMMP State
targeted by
MMMP Molecule
CD13
MMMP Molecule Alias
Aminopeptidase N
MMMP Modifier
NGR peptide
MMMP Relationship
sensitivity to
MMMP Drug
Doxorubicin
MMMP Drug Alias
Adriamycin (R)
MMMP Model
2
MMMP Reference
Sacchi A, Cancer Res 2004, 64:7150-5
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
DoxorubicinSensitivitytrue