Annotation Detail
Information
- Associated Genes
- HDAC9
- Associated Variants
- HDAC9 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- In this phase I trial (dose finding) both melanoma (n=6) and non-melanoma (n=26) patients were enrolled; the two partial responses were observed in non-melanoma patients
- MMMP State
- inhibited by
- MMMP Molecule
- HDAC
- MMMP Molecule Alias
- Histone deacetylase
- MMMP Modifier
- Vorinostat
- MMMP Relationship
- no relationship with
- MMMP Drug
- Doxorubicin
- MMMP Drug Alias
- Adriamycin (R)
- MMMP Model
- 5
- MMMP Reference
- Munster PN, Br J Cancer 2009, 101:1044-50
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Doxorubicin | Resitance or Non-Reponse | true |