Annotation Detail
Information
- Associated Genes
- XIAP
- Associated Variants
- XIAP UNDEREXPRESSION
- Source Database
- MMMP
- Description
- UVB cause XIAP degradation, which enhances TRAIL effect. Quite unexpectedly, UVB sensitization is mediated by NFkB, which mediates XIAP downregulation
- MMMP State
- inhibited by
- MMMP Molecule
- XIAP
- MMMP Modifier
- UVB
- MMMP Modifier Alias
- Ultraviolet B light
- MMMP Relationship
- sensitivity to
- MMMP Drug
- TRAIL
- MMMP Model
- 3
- MMMP Reference
- Thayaparasingham B, Oncogene 2009, 28:345-62
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| TRAIL | Sensitivity | true |