Annotation Detail
Information
- Associated Genes
- VEGFA
- Associated Variants
- VEGFA UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Erlotinib: small molecule inhibitor of EGFR. In vivo, in a severe combined immunodeficient mouse xenotransplantation model, reduction in tumor volume under combined treatment with erlotinib and bevacizumab was superior to the additive effect of both single agents
- MMMP State
- inhibited by
- MMMP Molecule
- VEGF
- MMMP Molecule Alias
- Vascular endothelial growth factor
- MMMP Modifier
- Bevacizumab
- MMMP Modifier Alias
- Avastin (R)
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Erlotinib
- MMMP Drug Alias
- Tarceva (R)
- MMMP Model
- 4
- MMMP Reference
- Schicher N, Clin Cancer Res 2009, 15:3495-502
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Erlotinib | Sensitivity | true |