Annotation Detail
Information
- Associated Genes
- VEGFA
- Associated Variants
- VEGFA UNDEREXPRESSION
- Source Database
- MMMP
- Description
- In this phase II trial (metastatic melanoma), bevacizumab + carboplatin + paclitaxel yielded partial response in 17% of cases and stable disease in 30% of cases
- MMMP Molecule
- VEGF
- MMMP State
- inhibited by
- MMMP Molecule Alias
- Vascular endothelial growth factor
- MMMP Modifier
- Bevacizumab
- MMMP Modifier Alias
- Avastin (R)
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Paclitaxel + Carboplatin
- MMMP Model
- 5
- MMMP Reference
- Perez DG, Cancer 2009, 115:119-27
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Paclitaxel + Carboplatin | Sensitivity | true |