Annotation Detail
Information
- Associated Genes
- BCL2
- Associated Variants
- BCL2 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- MG-132: proteasome inhibitor. ABT-737 combined with MG-132 synergistically induced Noxa-dependent mitochondrial-mediated apoptosis
- MMMP State
- inhibited by
- MMMP Molecule
- Bcl-2, Bcl-xL, Bcl-W
- MMMP Modifier
- ABT-737
- MMMP Relationship
- sensitivity to
- MMMP Drug
- MG-132
- MMMP Drug Alias
- Proteasome inhibitor
- MMMP Model
- 3
- MMMP Reference
- Miller LA, J Invest Dermatol 2009, 129:964-71
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| MG-132 | Sensitivity | true |