Annotation Detail
Information
- Associated Genes
- BCL2
- Associated Variants
- BCL2 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Bcl-2 and glutathione depletion sensitizes B16 melanoma to combination therapy and eliminates metastatic disease in vivo
- MMMP State
- downregulated by
- MMMP Molecule
- Bcl-2, GSH
- MMMP Modifier
- Oblimersen + anti-GSH diet
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Paclitaxel + TNF + IFN gamma + Radiotherapy
- MMMP Model
- 2
- MMMP Reference
- Mena S, Clin Cancer Res 2007, 13:2658-66
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Paclitaxel + TNF + IFN gamma + Radiotherapy | Sensitivity | true |