Annotation Detail
Information
- Associated Genes
- BCL2
- Associated Variants
- BCL2 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Lowering the apoptotic threshold enhances immune mediated melanoma cell lysis. ABT-737 does not inhibit Mcl-1
- MMMP State
- inhibited by
- MMMP Molecule
- Bcl-2, Bcl-xL
- MMMP Modifier
- ABT-737
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Lysis by cytotoxic T lymphocytes (CTL)
- MMMP Drug Alias
- MMMP Model
- 3
- MMMP Reference
- Lickliter JD, Br J Cancer 2007, 96:600-8
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Lysis by cytotoxic T lymphocytes (CTL) | Sensitivity | true |