Annotation Detail

Information
Associated Genes
ATM
Associated Variants
ATM UNDEREXPRESSION
Source Database
MMMP
Description
Suppression of ATM-dependent and STAT3-mediated antiapoptotic pathway sensitizes human melanoma cells to TRAIL-mediated apoptosis
MMMP State
inhibited by
MMMP Molecule
ATM
MMMP Molecule Alias
Ataxia telangiectasia mutated (kinase)
MMMP Modifier
KU-55933
MMMP Relationship
sensitivity to
MMMP Drug
TRAIL
MMMP Model
3
MMMP Reference
Ivanov VN, Cancer Res 2009, 69:3510-9
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
TRAILSensitivitytrue