Annotation Detail

Information
Associated Genes
VEGFA
Associated Variants
VEGFA UNDEREXPRESSION
Source Database
MMMP
Description
Experiments show a successful VEGF antibody based combination therapy with cisplatin and suggests that the enhancement of antitumor activity could be explained by a concomitant effect on both endothelial and tumor cell compartment
MMMP State
inhibited by
MMMP Molecule
VEGF
MMMP Molecule Alias
Vascular endothelial growth factor
MMMP Modifier
VEGF antibody (antagonist)
MMMP Relationship
sensitivity to
MMMP Drug
Cisplatin
MMMP Drug Alias
CDDP
MMMP Model
2
MMMP Reference
Ghosh S, Int Immunopharmacol 2007, 7:1598-608
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
CisplatinSensitivitytrue