Annotation Detail

Information
Associated Genes
XIAP
Associated Variants
XIAP UNDEREXPRESSION
Source Database
MMMP
Description
SMAC mimetics are SMAC derived peptides (SMAC physiologically inhibits antiapoptotic factor XIAP)
MMMP State
inhibited by
MMMP Molecule
XIAP
MMMP Modifier
SMAC mimetic
MMMP Relationship
sensitivity to
MMMP Drug
TRAIL
MMMP Model
3
MMMP Reference
Fulda S, Nat Med 2002, 8:808-15
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
TRAILSensitivitytrue