Annotation Detail
Information
- Associated Genes
- ABCB5
- Associated Variants
- ABCB5 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Besides expression/sensitivity correlation, ABCB5 inhibition (by a neutralizing antibody) leads to increased sensitivity to doxorubicin
- MMMP State
- inhibited by
- MMMP Molecule
- ABCB5
- MMMP Modifier
- ABCB5 antibody (antagonist)
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Doxorubicin
- MMMP Drug Alias
- Adriamycin (R)
- MMMP Model
- 3
- MMMP Reference
- Frank NY, Cancer Res 2005, 65:4320-33
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Doxorubicin | Sensitivity | true |