Annotation Detail
Information
- Associated Genes
- TNFRSF10A
- Associated Variants
- TNFRSF10A OVEREXPRESSION
- Source Database
- MMMP
- Description
- Reexpressing DR4 by 5-AZAdC in melanoma cells in which promoter methylation had suppressed its expression, potentiates apoptosis by IFN-alpha2b, IFN-beta and Apo2L/TRAIL
- MMMP State
- upregulated by
- MMMP Molecule
- TRAILR1
- MMMP Molecule Alias
- DR4
- MMMP Modifier
- Decitabine
- MMMP Modifier Alias
- 5-aza-2'-deoxycytidine
- MMMP Relationship
- sensitivity to
- MMMP Drug
- TRAIL
- MMMP Model
- 3
- MMMP Reference
- Bae SI, Oncogene 2008, 27:490-8
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| TRAIL | Sensitivity | true |