Annotation Detail
Information
- Associated Genes
- MGMT
- Associated Variants
- MGMT UNKNOWN
- Source Database
- MMMP
- Description
- MGMT causes resistance to TMZ
- MMMP State
- demethylated by
- MMMP Molecule
- MGMT
- MMMP Molecule Alias
- O-6-methylguanine-DNA methyltransferase
- MMMP Modifier
- 5-azacytidine
- MMMP Modifier Alias
- 5-AZA
- MMMP Relationship
- resistance to
- MMMP Drug
- Temozolomide
- MMMP Drug Alias
- TMZ
- MMMP Model
- 3
- MMMP Reference
- Fontijn D, Mol Cancer Ther 2007, 6:2807-15
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Temozolomide | Resitance or Non-Reponse | true |