Annotation Detail
Information
- Associated Genes
- MCL1
- Associated Variants
- MCL1 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- ABT-737 on its own was ineffective in melanoma cells unless Mcl-1 was experimentally downregulated
- MMMP State
- downregulated by
- MMMP Molecule
- Mcl-1
- MMMP Molecule Alias
- MMMP Modifier
- Mcl-1 siRNA
- MMMP Relationship
- sensitivity to
- MMMP Drug
- ABT-738
- MMMP Drug Alias
- Bcl-2 inhibitor
- MMMP Model
- 3
- MMMP Reference
- Weber A, Transl Oncol 2009, 2:73-83
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| ABT-738 | Sensitivity | true |