Annotation Detail
Information
- Associated Genes
- NRAS
- Associated Variants
- NRAS Q61L
- Source Database
- MMMP
- Description
- In vivo, the double BRAF and PI3K (PIK3CA) silencing obtained significant decrease in tumor growth
- MMMP State
- mut Q61L
- MMMP Molecule
- NRAS
- MMMP Molecule Alias
- N-Ras
- MMMP Relationship
- sensitivity to
- MMMP Drug
- PI3K siRNA + BRAF siRNA
- MMMP Model
- 4
- MMMP Reference
- Jaiswal BS, PLoS One 2009, 4:e5717
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| PI3K siRNA + BRAF siRNA | Sensitivity | true |