Annotation Detail

Information
Associated Genes
NRAS
Associated Variants
NRAS Q61L
Source Database
MMMP
Description
Silencing of MEK1, MEK2 or both did not affect proliferation of melanoma cells harboring this NRAS mutation
MMMP State
mut Q61L
MMMP Molecule
NRAS
MMMP Molecule Alias
N-Ras
MMMP Relationship
no relationship with
MMMP Drug
MEK siRNA
MMMP Model
3
MMMP Reference
Jaiswal BS, PLoS One 2009, 4:e5717
MMMP DNA/mRNA/Protein
DNA
Drugs
Drug NameSensitivitySupported
MEK siRNAResitance or Non-Reponsetrue