Annotation Detail
Information
- Associated Genes
- NRAS
- Associated Variants
- NRAS Q61L
- Source Database
- MMMP
- Description
- In vitro the CRAF-shRNA expressing IPC298 cells showed a 20% decrease in proliferation: however, in vivo, CRAF silencing did not show a statistically significant delay in IPC298 tumor growth
- MMMP State
- mut Q61L
- MMMP Molecule
- NRAS
- MMMP Molecule Alias
- N-Ras
- MMMP Relationship
- no relationship with
- MMMP Drug
- CRAF siRNA
- MMMP Model
- 4
- MMMP Reference
- Jaiswal BS, PLoS One 2009, 4:e5717
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| CRAF siRNA | Resitance or Non-Reponse | true |