Annotation Detail

Information
Associated Genes
MGMT
Associated Variants
MGMT METHYLATION
Source Database
MMMP
Description
Uveal melanoma. These results do not support MGMT methylation status or protein expression as predictive markers for treatment outcome to intra-arterial chemotherapy with alkylating agents
MMMP State
methylated
MMMP Molecule
MGMT
MMMP Molecule Alias
O-6-methylguanine-DNA methyltransferase
MMMP Relationship
no relationship with
MMMP Drug
Fotemustine
MMMP Model
5
MMMP Reference
Voelter V et al, Int J Cancer 2008, 123:1215-8
MMMP DNA/mRNA/Protein
DNA
Drugs
Drug NameSensitivitySupported
FotemustineResitance or Non-Reponsetrue