Annotation Detail
Information
- Associated Genes
- KRAS
- Associated Variants
- KRAS G12V
- Source Database
- MMMP
- Description
- KIT inhibitor imatinib works against KIT mutant-transformed melanocytes but not against KIT wild type or KRAS mutated melanocytes
- MMMP State
- mut G12V
- MMMP Molecule
- KRAS
- MMMP Molecule Alias
- K-Ras
- MMMP Relationship
- no relationship with
- MMMP Drug
- Imatinib
- MMMP Drug Alias
- Gleevec (R)
- MMMP Model
- 1
- MMMP Reference
- Monsel G, Oncogene 2010, 29:227-36
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Imatinib | Resitance or Non-Reponse | true |