Annotation Detail
Information
- Associated Genes
- IL1A
- Associated Variants
-
IL1A MUTATION
IL1A MUTATION - Associated Disease
- renal cell carcinoma
- Source Database
- DisGeNET
- Description
- Indeed, targeting of IL-1-IL-1R axis in a human RCC xenograft model abrogated the protumor phenotype of tumor-associated macrophages (TAMs) and reduced tumor growth in vivo.
- Pubmed
- 25453823
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 5
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.00290991572276264
Drugs