Annotation Detail

Information
Associated Genes
VHL
Associated Variants
VHL MUTATION
VHL MUTATION
Associated Disease
renal cell carcinoma
Source Database
DisGeNET
Description
The small-molecule probes STF-31 and its analogue compound 146 were discovered while searching for compounds that kill VHL-deficient renal cell carcinoma cell lines selectively and have been reported to act via direct inhibition of the glucose transporter GLUT1.
Pubmed
25058389
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,LHGDN
DisGENET score for the Gene Disease association
0.239057832796053
Drugs