Annotation Detail

Information
Associated Genes
CASP9
Associated Variants
CASP9 MUTATION
CASP9 MUTATION
Associated Disease
Non-small cell lung carcinoma
Source Database
DisGeNET
Description
Matrine caused apoptotic death in the cisplatin-resistant NSCLC cells, coupled with loss of ΔΨm and activation of caspase-9 and -3.
Pubmed
25760455
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00162865123248182
Drugs