Annotation Detail
Information
- Associated Genes
- MET
- Associated Variants
-
MET MUTATION
MET MUTATION - Associated Disease
- Non-small cell lung carcinoma
- Source Database
- DisGeNET
- Description
- Expression of the oncogene hepatocyte growth factor receptor (MET) and phosphorylation of the MET protein have been associated with both primary and acquired resistance to tyrosine kinase inhibitors (TKIs) used in therapy targeting the epidermal growth factor receptor (EGFR) in patients with non-small cell lung cancers (NSCLCs).
- Pubmed
- 25522678
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree,CTD_human
- DisGENET score for the Gene Disease association
- 0.141443907894344
Drugs