Annotation Detail
Information
- Associated Genes
- MET
- Associated Variants
-
MET MUTATION
MET MUTATION - Associated Disease
- Non-small cell lung carcinoma
- Source Database
- DisGeNET
- Description
- Similar to EGFR mutations, ALK rearrangements exemplify an oncogene-driven NSCLC that can be effectively palliated with a precision TKI therapy (the multitargeted ALK/MET/ROS1 TKI crizotinib).
- Pubmed
- 24857124
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree,CTD_human
- DisGENET score for the Gene Disease association
- 0.141443907894344
Drugs