Annotation Detail
Information
- Associated Genes
- UCN3
- Associated Variants
-
UCN3 MUTATION
UCN3 MUTATION - Associated Disease
- Non-small cell lung carcinoma
- Source Database
- DisGeNET
- Description
- In conclusion, negative modulation of EGFR signaling by the chimeric ubiquitin ligases can inhibit malignancy of SPC-A1 cells and sensitize these cells to chemotherapy, thus it may be applied to targeted therapy for NSCLC.
- Pubmed
- 25573345
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00325730246496364
Drugs