Annotation Detail

Information
Associated Genes
EIF4EBP1
Associated Variants
EIF4EBP1 MUTATION
EIF4EBP1 MUTATION
Associated Disease
Non-small cell lung carcinoma
Source Database
DisGeNET
Description
In addition, this study showed that NUAK1 influenced mTOR phosphorylation and induced the phosphorylation of p70S6K1 and eukaryotic initiation factor 4E-binding protein1 (4E-BP1), two downstream targets of mTOR in NSCLC cells.
Pubmed
25412236
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
14
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00108576748832121
Drugs