Annotation Detail

Information
Associated Genes
BRAF
Associated Variants
BRAF MUTATION
BRAF MUTATION
Associated Disease
Rectal Carcinoma
Source Database
DisGeNET
Description
Compared with BRAF wild type, BRAF(V600E) was a risk for poor survival (overall survival; 5 years: 62.3% vs 51.6%, P=0.014; HR 1.43, CI 1.07-1.90, P=0.009), especially in rectal cancer (for DSS, HR: 10.60, CI: 3.04-36.92, P<0.001).
Pubmed
25973534
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0077199245500874
Drugs