Annotation Detail
Information
- Associated Genes
- CDX2
- Associated Variants
-
CDX2 MUTATION
CDX2 MUTATION - Associated Disease
- Malignant tumor of colon
- Source Database
- DisGeNET
- Description
- The homeoprotein encoded by the intestinal-specific Cdx2 gene is a major regulator of gut development and homeostasis, also involved in colon cancer as well as in intestinal-type metaplasias when it is abnormally expressed outside the gut.
- Pubmed
- 25663763
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00760037241824849
Drugs