Annotation Detail
Information
- Associated Genes
- IL1B
- Associated Variants
-
IL1B MUTATION
IL1B MUTATION - Associated Disease
- Malignant neoplasm of breast
- Source Database
- DisGeNET
- Description
- Here, we identified the impact of TNF-α and IL-1β on the inflammatory phenotype of CAFs and MSCs by determining the expression of inflammatory chemokines that are well-characterized as pro-tumorigenic in breast cancer: CCL2 (MCP-1), CXCL8 (IL-8) and CCL5 (RANTES).
- Pubmed
- 25928089
- Section of the abstract supporting the evidence
- INTRODUCTION
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 3
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.0338332211848304
Drugs