Annotation Detail
Information
- Associated Genes
- LTA
- Associated Variants
-
LTA p.Cys13Arg (p.C13R)
(
ENST00000454783.5,
ENST00000418386.3 )
LTA p.Thr60Asn (p.T60N) ( ENST00000454783.5, ENST00000418386.3 )
LTA p.Cys13Arg (p.C13R) ( ENST00000418386.3, ENST00000454783.5 )
LTA p.Thr60Asn (p.T60N) ( ENST00000418386.3, ENST00000454783.5 ) - Associated Disease
- Cardiovascular Diseases
- Source Database
- DisGeNET
- Description
- In this clinical study, the influence of genetic variants of TNF-beta (c.7G>A, IVS1+90G>A, C13R, T60N) on major coronary risk factors, including gender, smoking, history of cardiovascular diseases, biochemical data (inflammatory markers, factors of lipid metabolism, coagulation/fibrinolysis balance), and angiographically-proven coronary state, was investigated in 176 European Caucasian probands (130 males, mean age: 51.9 +/- 8.9 y).
- Pubmed
- 17194634
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.007915421552047
- Year of publication
- 2006
Drugs