Annotation Detail

Information
Associated Genes
PIK3CB
Associated Variants
PIK3CB MUTATION
PIK3CB MUTATION
Associated Disease
Malignant neoplasm of breast
Source Database
DisGeNET
Description
Direct inhibition of PI3K in combination with dual HER2 inhibitors is required for optimal antitumor activity in HER2+ breast cancer cells.
Pubmed
24451154
Section of the abstract supporting the evidence
TITLE
Number of the section of the abstract supporting the evidence
0
Number of the sentence supporting the evidence
0
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0466120571276915
Drugs