Annotation Detail

Information
Associated Genes
ABCG2
Associated Variants
ABCG2 MUTATION
ABCG2 MUTATION
Associated Disease
Malignant neoplasm of breast
Source Database
DisGeNET
Description
Inhibition or upregulation of HIF-1α affects breast cancer cell expression of BCRP; AI responsiveness; and expression of cancer stem cell characteristics, partially through BCRP.
Pubmed
24472707
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
12
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0171008379410591
Drugs