Annotation Detail

Information
Associated Genes
PHRF1
Associated Variants
PHRF1 c.421-1820T>C ( ENST00000533464.5, ENST00000416188.3, ENST00000264555.10, ENST00000413872.6 )
IRF7 p.Gln425Arg (p.Q425R) ( ENST00000397570.5, ENST00000525445.6, ENST00000397566.5, ENST00000330243.9, ENST00000348655.11 )
PHRF1 c.421-1820T>C ( ENST00000264555.10, ENST00000413872.6, ENST00000416188.3, ENST00000533464.5 )
IRF7 p.Gln425Arg (p.Q425R) ( ENST00000330243.9, ENST00000348655.11, ENST00000397566.5, ENST00000397570.5, ENST00000525445.6 )
Associated Disease
Lupus Erythematosus, Systemic
Source Database
DisGeNET
Description
We genotyped one KIAA1542 SNP (rs4963128) and one IRF7 SNP (rs1131665 [Q412R]) in an Asian population (1,302 cases, 1,479 controls), to assess their association with SLE.
Pubmed
21360504
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.256188161367959
Year of publication
2011
Drugs