Annotation Detail
Information
- Associated Genes
- TLR4
- Associated Variants
-
TLR4 MUTATION
TLR4 MUTATION - Associated Disease
- atherosclerosis
- Source Database
- DisGeNET
- Description
- The results of our in silico analysis in vitro provide potential evidence that STAT1-dependent IFNγ-TLR4 cross-talk plays a crucial role in coronary and carotid artery plaque development and identifies a STAT1-dependent gene signature that could represent a novel diagnostic tool to monitor and diagnose plaque progression in human atherosclerosis.
- Pubmed
- 25196434
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree,CTD_human,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.158128802701335
Drugs