Annotation Detail
Information
- Associated Genes
- IL23R
- Associated Variants
-
IL23R p.Leu310Pro (p.L310P)
(
ENST00000697154.1,
ENST00000371007.6,
ENST00000347310.10,
ENST00000425614.3,
ENST00000697165.1,
ENST00000697164.1,
ENST00000697230.1,
ENST00000697163.1 )
IL23R p.Arg381Gln (p.R381Q) ( ENST00000697230.1, ENST00000697164.1, ENST00000697163.1, ENST00000697154.1, ENST00000425614.3, ENST00000347310.10, ENST00000697165.1 )
IL12B c.*159A>C ( ENST00000231228.3, ENST00000696750.1 )
rs6887695
IL6 c.-84-153C>G ( ENST00000404625.5 )
IL23R p.Leu310Pro (p.L310P) ( ENST00000347310.10, ENST00000425614.3, ENST00000697154.1, ENST00000697163.1, ENST00000697164.1, ENST00000697165.1, ENST00000697230.1, ENST00000371007.6 )
IL23R p.Arg381Gln (p.R381Q) ( ENST00000347310.10, ENST00000425614.3, ENST00000697154.1, ENST00000697163.1, ENST00000697164.1, ENST00000697165.1, ENST00000697230.1 )
IL12B c.*159A>C ( ENST00000231228.3, ENST00000696750.1 )
rs6887695
IL6 c.-84-153C>G ( ENST00000404625.5 ) - Associated Disease
- psoriasis
- Source Database
- DisGeNET
- Description
- This study aims to assess whether the association between the non-susceptibility allelic variants of IL12B single-nucleotide polymorphism (SNPs) rs3212227 and rs6887695, IL23R SNPs rs11209026 and rs7530511, IL6 SNP rs1800795 and HLA-Cw6 could be correlated with decreased risk for psoriasis.
- Pubmed
- 24140476
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.310524988480582
- Year of publication
- 2013
Drugs