Annotation Detail

Information
Associated Genes
IL23R
Associated Variants
IL23R p.Leu310Pro (p.L310P) ( ENST00000697154.1, ENST00000371007.6, ENST00000347310.10, ENST00000425614.3, ENST00000697165.1, ENST00000697164.1, ENST00000697230.1, ENST00000697163.1 )
IL23R p.Arg381Gln (p.R381Q) ( ENST00000697230.1, ENST00000697164.1, ENST00000697163.1, ENST00000697154.1, ENST00000425614.3, ENST00000347310.10, ENST00000697165.1 )
IL23R p.Leu310Pro (p.L310P) ( ENST00000347310.10, ENST00000425614.3, ENST00000697154.1, ENST00000697163.1, ENST00000697164.1, ENST00000697165.1, ENST00000697230.1, ENST00000371007.6 )
IL23R p.Arg381Gln (p.R381Q) ( ENST00000347310.10, ENST00000425614.3, ENST00000697154.1, ENST00000697163.1, ENST00000697164.1, ENST00000697165.1, ENST00000697230.1 )
Associated Disease
ulcerative colitis
Source Database
DisGeNET
Description
The results suggest that IL23R R381Q confers protection against CD and that L310P confers protection against UC in females.
Pubmed
19294505
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.326936272243952
Year of publication
2010
Drugs