Annotation Detail
Information
- Associated Genes
- IL13
- Associated Variants
-
IL13 MUTATION
IL13 MUTATION - Associated Disease
- asthma
- Source Database
- DisGeNET
- Description
- Type 2 innate lymphoid cells (ILC2s) are a newly identified subset of immune cells that, along with Th2 cells, contribute to the pathogenesis of asthma by producing copious amounts of IL-5 and IL-13, which cause eosinophilia and airway hyperreactivity (AHR), a cardinal feature of asthma.
- Pubmed
- 25769613
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree,CTD_human,GAD,GWASCAT,LHGDN,RGD
- DisGENET score for the Gene Disease association
- 0.490519253184375
Drugs