Annotation Detail
Information
- Associated Genes
- ALOX5
- Associated Variants
-
ALOX5 MUTATION
ALOX5 MUTATION - Associated Disease
- asthma
- Source Database
- DisGeNET
- Description
- The 5-lipoxygenase product 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) is the most powerful human eosinophil chemoattractant among lipid mediators and could play a major pathophysiological role in eosinophilic diseases such as asthma.
- Pubmed
- 26032638
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree,CTD_human,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.170821895472305
Drugs