Annotation Detail

Information
Associated Genes
MMP9
Associated Variants
MMP9 MUTATION
MMP9 MUTATION
Associated Disease
rheumatoid arthritis
Source Database
DisGeNET
Description
The synthesis and secretion of MMP-9 can be stimulated by a variety of stimuli, including cytokines and phorbol 12-myristate 13-acetate (PMA), during various pathological processes, such as tumor invasion, atherosclerosis, inflammation, and rheumatoid arthritis, whereas MMP-2 is usually expressed constitutively.
Pubmed
25000305
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0120729260250364
Drugs