Annotation Detail

Information
Associated Genes
ALOX5
Associated Variants
ALOX5 MUTATION
ALOX5 MUTATION
Associated Disease
rheumatoid arthritis
Source Database
DisGeNET
Description
The lipoxygenase isoform of 5-lipoxygenase (5-LOX) is reported to be overexpressed in human rheumatoid arthritis synovial tissue and involved in the progress of inflammatory arthritis.
Pubmed
25229347
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree,CTD_human
DisGENET score for the Gene Disease association
0.121085767488321
Drugs