Annotation Detail
Information
- Associated Genes
- IL1B
- Associated Variants
-
IL1B MUTATION
IL1B MUTATION - Associated Disease
- rheumatoid arthritis
- Source Database
- DisGeNET
- Description
- The pro-inflammatory cytokine interleukin (IL)-1β is a clinical target in many conditions involving dysregulation of the immune system; therapeutics that block IL-1β have been approved to treat diseases such as rheumatoid arthritis (RA), neonatal onset multisystem inflammatory diseases, cryopyrin-associated periodic syndromes, active systemic juvenile idiopathic arthritis.
- Pubmed
- 24671001
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree,CTD_human,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.238168069401454
Drugs