Annotation Detail
Information
- Associated Genes
- ALOX5
- Associated Variants
-
ALOX5 MUTATION
ALOX5 MUTATION - Associated Disease
- arthritis
- Source Database
- DisGeNET
- Description
- Our results provide the evidence that the administration of 5-LOX inhibitors is able to ameliorate TNF-α-induced cytokine/chemokine release and paw edema, indicating that 5-LOX inhibitors may be developed for therapeutic treatment of inflammatory arthritis.
- Pubmed
- 25229347
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 12
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs