Annotation Detail
Information
- Associated Genes
- TNF
- Associated Variants
-
TNF MUTATION
TNF MUTATION - Associated Disease
- arteriosclerosis
- Source Database
- DisGeNET
- Description
- Furthermore, sortilin also seems to be involved in the development of atherosclerosis, by mechanisms not directly involving LDL-cholesterol, but possibly resulting from the attenuated secretion of proinflammatory cytokines, such as IL6 and TNFα, which accompanies lack of sortilin in immune cells.
- Pubmed
- 25702058
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 5
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0160150704527379
Drugs