Annotation Detail

Information
Associated Genes
IL1B
Associated Variants
IL1B MUTATION
IL1B MUTATION
Associated Disease
aortic aneurysm
Source Database
DisGeNET
Description
Analysis of gene expression using real-time polymerase chain reaction (PCR) revealed significantly increased median mRNA levels of the inflammasome core components PYCARD (ASC), CASP1 (Caspase-1) and IL1B (IL-1β) in AAA tissue compared with normal aorta.
Pubmed
24618883
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs