Annotation Detail

Information
Associated Genes
HBB
Associated Variants
HBB MUTATION
HBB MUTATION
Associated Disease
Anemia, Sickle Cell
Source Database
DisGeNET
Description
SCD-corrected hiPSC lines showed gene conversion of the mutated βS to the wild-type βA in one of the HBB alleles, while the other allele remained a mutant phenotype.
Pubmed
25245091
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree,CLINVAR,CTD_human,GAD,LHGDN,ORPHANET,UNIPROT
DisGENET score for the Gene Disease association
0.577859960475621
Drugs