Annotation Detail
Information
- Associated Genes
- OR2H2
- Associated Variants
-
OR2H2 MUTATION
OR2H2 MUTATION
OR2H2 c.*99C>T ( ENST00000355973.7, ENST00000641840.1 )
ATF6B c.*216T>C ( ENST00000375201.8, ENST00000375203.8, ENST00000453203.2 )
rs7769979
OR2H2 c.*99C>T ( ENST00000355973.7, ENST00000641840.1 )
ATF6B c.*216T>C ( ENST00000375201.8, ENST00000375203.8, ENST00000453203.2 )
rs7769979 - Associated Disease
- Lupus Erythematosus, Systemic
- Source Database
- DisGeNET
- Description
- Sequential removal of SLE-associated DRB1 haplotypes revealed independent effects due to variation within OR2H2 (extended class I, rs362521, p = 0.006), CREBL1 (class III, rs8283, p = 0.01), and DQB2 (class II, rs7769979, p = 0.003, and rs10947345, p = 0.0004).
- Pubmed
- 19851445
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00263847385068233
- Year of publication
- 2009
Drugs