Annotation Detail

Information
Associated Genes
APOE
Associated Variants
APOE MUTATION
APOE MUTATION
Associated Disease
amyotrophic lateral sclerosis
Source Database
DisGeNET
Description
Treatment of adult microglia with apolipoprotein E suppressed the M0-homeostatic unique microglia signature and induced an M1-like phenotype. miR-155 expression was increased in the spinal cord of both familial and sporadic ALS.
Pubmed
25381879
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0174594943365758
Drugs