Annotation Detail

Information
Associated Genes
ADAMTS9
Associated Variants
rs12779790
TSPAN8 c.-110+8029G>A ( ENST00000393330.6 )
NOTCH2 c.875-5592C>A ( ENST00000256646.7 )
THADA p.Thr1187Ala (p.T1187A) ( ENST00000405006.8, ENST00000405975.7 )
rs4607103
JAZF1 c.115+39526A>G ( ENST00000283928.10 )
rs12779790
TSPAN8 c.-110+8029G>A ( ENST00000393330.6 )
NOTCH2 c.875-5592C>A ( ENST00000256646.7 )
THADA p.Thr1187Ala (p.T1187A) ( ENST00000405006.8, ENST00000405975.7 )
rs4607103
JAZF1 c.115+39526A>G ( ENST00000283928.10 )
Associated Disease
Diabetes
Source Database
DisGeNET
Description
We evaluated the impact on diabetes-related intermediary traits of common novel type 2 diabetes-associated variants in the JAZF1 (rs864745), CDC123/CAMK1D (rs12779790), TSPAN8 (rs7961581), THADA (rs7578597), ADAMTS9 (rs4607103), and NOTCH2 (rs10923931) loci, which were recently identified by meta-analysis of genome-wide association data.
Pubmed
18567820
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2008
Drugs