Annotation Detail

Information
Associated Genes
TMEM18
Associated Variants
SEC16B c.1881+177A>G ( ENST00000308284.11 )
rs2867125
NC_000002.12:g.634905T>C
rs4854344
rs7561317
SEC16B c.1881+177A>G ( ENST00000308284.11 )
rs2867125
NC_000002.12:g.634905T>C
rs4854344
rs7561317
Associated Disease
obesity
Source Database
DisGeNET
Description
The SNP rs10913469 in SEC16B (P=0.000012) and four SNPs (rs2867125, rs6548238, rs4854344 and rs7561317) in the TMEM18 gene (P=0.00015), all of which were in almost absolute linkage disequilibrium, were significantly associated with obesity in the Japanese population.
Pubmed
19851340
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.162215581610917
Year of publication
2009
Drugs